Susan M. Quirk - Associate Professor
PhD from Cornell University
Graduate fields: Animal Science, Physiology
Area(s) of interest: ovarian physiology, molecular biology.
Teaching:
Professional Organizations:
Email: smq1@cornell.edu
Current Research
Ovarian Physiology (More Information)
Studies focused on:
- Regulation of pathways for programmed cell death, or apoptosis, as a mechanism for follicular atresia.
- Interaction among pathways regulating cell proliferation and apoptosis.
- Regulation of apoptosis during regression of the corpus luteum.
- Role of the hedgehog signaling pathway in ovarian development and function.
- Regulation of the ovarian surface epithelium.
Current funding: National Institutes of Health, U.S. Department of Agriculture
Selected Recent Publications:
Russell, MC, Cowan, RG, Harman, RM, Walker, AL and Quirk, SM. 2007. The hedgehog signaling pathway in the mouse ovary. Biology of Reproduction 77:226-236.
Quirk, SM, Cowan, RG, Harman, RM. 2006. The susceptibility of granulosa cells to apoptosis is influenced by oestradiol and the cell cycle. Journal of Endocrinology 189:441-443.
Margalit, KA, Cowan, RG, Harman, RM, Quirk, SM. 2005. Apoptosis of bovine ovarian surface epithelial cells by Fas antigen/Fas ligand signaling. Reproduction 130:751-758. Hu, C-L, Cowan, RG, Harman, RM, Quirk, SM. 2004. Cell cycle progression and activation of Akt kinase are required for IGF-mediated suppression of apoptosis in granulosa cells. Molecular Endocrinology 18: 326-338.
Quirk, SM, Cowan, RG, Harman, RM. 2004. Progesterone receptor and the cell cycle modulate apoptosis in granulosa cells. Endocrinology 145: 5033-5043.
Quirk, SM, Cowan, RG, Harman, RM, Hu, C-L, Porter, DA. 2004. Ovarian follicular growth and atresia: the relationship between cell proliferation and survival. J. Animal Science 82(E. Suppl.):E40-E52.